Development and implementation of genetically encoded probes for monitoring critical quality attributes in bioprocesses

A Ph.D. project is offered within the research teams of Professor Marie-Eve Paquet (Department of Biochemistry, Microbiology, and Bioinformatics) and Professor Younès Messaddeq (Department of Physics, Physical Engineering, and Optics). Both teams are part of the Canadian Optogenetics and Vectorology Foundry (COVF), a national facility at the heart of a worldwide effort to accelerate the development, production, dissemination, and use of genetically encoded light-activated tools.

Supported by the Eastern Canada Pandemic Preparedness Hub (https://ecapph.openum.ca/en/), this project focuses on developing innovative strategies for quality monitoring of cell cultures used in the production of viral vectors and recombinant proteins. The research environment is enriched by strategic partnerships with governmental and industrial organizations, including the National Research Council of Canada (NRC), INO, and Ivano Biosciences.